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They might mediate a nausealinked reduction in food intake but might not be involved in mediating the sensation of feeling sick

"There are a number of others trying to break into [the market] both small and large, but when I step back, I do think that Amgen has a real shot at being disruptive and challenging Eli Lilly and Novo," William Blair & Company analyst Matt Phipps told CNBC

Novo Nordisk makes both Ozempic, which has been approved only for Type 2 diabetes, and its close relative Wegovy, which has been approved for weight loss

As your body adjusts to these signals, the intensity of appetite suppression and metabolic effects may gradually decrease, even if your dose stays constant