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These data suggest that GLP-1 receptors contribute to the insulinotropic action of glucagon and that in GLP-1R knockout mice there is some extrapancreatic mechanism that compensates for the loss of glucagon-induced insulin secretion via GLP-1R

Berberine Modulates LPA Function to Inhibit the Proliferation and Inflammation of FLS-RA via P38/ERK MAPK Pathway Mediated by LPA1. Evidence-Based Complementary and Alternative Medicine, vol

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Significance: The COVID-19 pandemic highlighted the importance of RWE, as regulators utilized RWD to monitor the safety and efficacy of treatments