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Avila-Aguero, Jose Brea Del Castillo, CARLOS ESPINAL, Rodrigo Romero Feregrino, Jaime Torres, Hebe Vazquez, Mdico Geriatra Robinson Cuadros, Dr

If genetic testing reveals low predicted responsiveness to GLP-1 alone, PlexusDx counselors discuss realistic expectations, combination peptide protocols, and the importance of long-term adherence rather than rushing to add risky off-label combinations

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Because Glp1r mRNA is also expressed in the human OB 53 , it is intriguing to explore in future studies whether intranasal administration of GLP-1 agonists 54 could potentially exert their effects by acting in the OB (a site of persistent sensitivity to GLP-1 in obesity according to our data)