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These signaling pathways are crucial for mediating the anorectic and neuroprotective effects of GLP-1R activation [22,23]

Multidrug and toxin extrusion proteins (MATE/SLC47)

This early dip is usually modest, clinically insignificant, and followed by long-term stabilisation and a slower decline in renal function, as observed with reninangiotensin system inhibitors

IV vitamin and nutrient therapy may offer symptomatic support for some patients when used alongside their prescribed medical regimen, but it is not a substitute for disease-modifying treatment