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A 2022 systematic review and meta-analysis in the American Journal of Clinical Nutrition pooled 16 randomized controlled trials (1,251 participants) and found psyllium the most efficacious fiber investigated for chronic constipation: it increased bowel movements by about 3 per week , improved stool consistency, and was the only fiber to significantly reduce straining

The overall risk in terms of how many patients are potentially affected is still very small, he notes

The Future of Joint Wellness The conversation around joint health is shifting toward cellular support

Others find that nausea compounds tamoxifen's GI side effects and requires slower titration or dose reduction