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Elevated homocysteine has been associated with cardiovascular disease, stroke, and impaired blood vessel function, making methylation an important contributor to cardiovascular health

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When it's missing, muscle can be harder to preserve, especially when overall intake is lower

Cancerous tissues demonstrate elevated expression of the vitamin D receptor (VDR), and both in vivo animal models and in vitro cell culture studies have shown that the active form of vitamin D, 1,25(OH)D, inhibits critical processes such as cell proliferation, angiogenesis, and tumour invasion, while also promoting cellular differentiation and apoptosis