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Potential consequences for the elderly include, for example, tissue damage, impaired immune responses (immunosuppressive microenvironment) and disrupted tissue environments, leading to the development of numerous age-related disorders [26, 29,30,31]

For a diagnosis of CVS, a child must meet all of the following criteria 7,9 : A minimum of five attacks in any period, or at least three attacks in 6 months

The SURPASS program (for type 2 diabetes) and SURMOUNT program (for obesity) together enrolled over 20,000 participants across multiple Phase III trials

Significant clinical improvement was observed in as short as 4 weeks, with enhanced quality of life by the 8th week (306)