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The VEGFR2-independent mechanism involves Src kinase-mediated phosphorylation of caveolin-1, disrupting the inhibitory interaction between caveolin-1 and eNOS

In this publication, we also found that MCT1 is highly enriched within oligodendrocytes and that transgenic or viral-mediated reduction of MCT1 either globally or selectively in oligodendrocytes causes axonal damage and neuronal loss in animal and cell culture models

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