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When your metabolism is healthy, you: Maintain stable energy throughout the day Burn fat efficiently Have healthy blood sugar regulation Maintain ideal body composition Experience mental clarity and focus Recover well from exercise Sleep restfully Age gracefully When your metabolism is dysfunctional, you experience: Weight gain and trouble losing weight despite diet and exercise Insulin resistance and elevated blood sugar Chronic fatigue and low energy Brain fog and poor concentration Increased belly fat (visceral adiposity) Poor exercise recovery Increased inflammation Accelerated aging Metabolic dysfunction is the root cause of most chronic diseases , including type 2 diabetes, cardiovascular disease, fatty liver disease, Alzheimers disease, and many cancers

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In pre-clinical research, inhibiting NNMT is studied for its effects on NAD+ salvage pathway activity and methyl-donor availability