glp-1 addiction medications get at the heart of addiction: study – WashU Medicine Five things to know about

glp-1 addiction

glp-1 addiction medications get at the heart of addiction: study – WashU Medicine Five things to know about

Name: glp-1 addiction medications get at the heart of addiction: study – WashU Medicine Five things to know about
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To minimize toxicity to normal tissues, DRP-104, a peptide prodrug of DON, was developed to preferentially convert DON in tumor tissues

Mechanistically, Beclin-1 binds to solute carrier family 7 member 11 (SLC7A11), a crucial part of system Xc-, inhibiting its action and subsequent ferroptosis through phosphorylating at ser90/93/96 (Song et al., 2018)