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[4] By contrast, patches often contain blends of herbal extracts, vitamins, amino acids, or stimulants marketed as supporting metabolism or boosting natural GLP-1 levels. This makes them dietary supplements rather than medications

Specifically, metformin attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration through the insulin-signaling pathway by inhibiting the expression of advanced glycation end product (AGEs) receptors, which are related to cancer mortality through AMPK [21,22]

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Remove the cap and inspect the medication for any particles or discoloration