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The exenatide group in this study, however, showed a significant increase in the mean cardiac output by 1.2 L/min, a reduced total peripheral resistance by the mean of 120 dyns/cm 5 , and a significantly reduced urinary sodium: creatinine ratio without a significant change in the BP [39]

Semaglutide targets one receptor, GLP-1 (glucagon-like peptide-1)

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Known for its strong efficacy in improving blood sugar control and promoting significant weight reduction, semaglutide has transformed many patient outcomes