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GLP-1 RAs and Their Possible Use for Addiction and Inflammatory Conditions

Clinical trials have demonstrated weight loss ranging from approximately 10% with GLP-1 agents at weight management doses (e.g., semaglutide 2.4 mg in the STEP trials) to over 20% with tirzepatide at higher doses (SURMOUNT trials)

Examples of variables associated with a higher or lower risk for treatment discontinuation for both drugs were age, place of birth, education, income and number of diabetes drugs used

An Ozempic lawsuit filed in either the gastrointestinal MDL or the vision loss litigation generally alleges that the drug manufacturers failed to adequately warn about the reported risks associated with these medications