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The Policy: Medicare's BALANCE Model In July 2026, Medicare launches the GLP-1 Bridge, an interim six-month pilot covering semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) for beneficiaries with a BMI of 30 or higher, or BMI of 27 or higher with an obesity-related comorbidity (diabetes, cardiovascular disease, hypertension)

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These neuromodulatory patterns are dose-, device-, and sex-dependent, indicating that delivery method (standard spray versus breath-powered nebulizer) and hormonal milieu shape brain penetration and response