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The authors found that acetyl-l-carnitine inhibited TNF--induced insulin resistance via activating AMPK signaling, thus increasing rates of skeletal muscle fatty-acid oxidation, leading to reduced malonyl-CoA and increased long chain fatty acyl-CoA flux into the mitochondria [53]

Kosiborod MN, Abildstrm SZ, Borlaug BA et al (2023) Semaglutide in patients with heart failure with preserved ejection fraction and obesity

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doi: 10.1016/j.tcb.2020.02.009 24 ChenXLiJKangRKlionskyDJTangD