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Taking matters into ones own hands by playing with dose sizes is a gamble: It might reduce side effects or costs in the short term, but it could also render the treatment ineffective or introduce new risks, all for unverified benefits

The positive effects of the diet are attributed to maintaining a state of nutritional ketosis, which is also a marker for compliance to the diet and assessed by elevated levels of ketone bodies such as acetoacetate in the urine, beta-hydroxybutyrate (BHB) in the blood, and acetone in the breath (7, 8)

PPAR- with its anti-inflammatory and anti-fibrotic action could be an effective therapeutic target in IBD

Although, PRKAR1A and GNAQ mutations coexist in the MMNST described herein, we found no other documentation of their coexistence in the entities discussed above [16, 20, 21, 23, 24, 25]