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Reports from patient experiences and post-marketing surveillance suggest that hair thinning or increased shedding may occur several months after initiating therapy, typically coinciding with periods of rapid weight loss

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A yellow color in these cases may be due to food moving too fast or not mixing with enough bile

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We validated the model internally and externally quantitatively by verifying that the adherence, HbA1c levels, and disutility of patient cohorts passing through the model matched the data used to estimate the model parameters

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