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Even in patients who have already begun to show symptoms, such as cardiomyopathy (a weakened, enlarged heart) or severe muscle weakness, L-carnitine therapy is frequently able to reverse the damage and return heart function to normal [1] [2] [6]

However, the positive predictive value of the diagnosis in the Swedish Patient Register was generally very high (ranging between 85 and 95%) based on the previous report [40]

Specifically, in the Type I group, they found negative correlations between age and behavior, possibly due to non-imprinted genes like CYFIP1

The SURMOUNT-1 trial provides the most comprehensive data