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Nicotinamide restores cognition in Alzheimers disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau

The MTT results revealed that [R5K]W7A-DOX conjugate (5 M) had no significant cytotoxicity to heart muscle cells and kidney cells compared to free DOX (5 M) obviously increasing the cell apoptosis and destroying the morphology of the cells after 72 h of incubation

[DOI] [Google Scholar] 112.Cummings J.L., Atri A., Feldman H.H., Hansson O., Sano M., Knop F.K., Johannsen P., Len T., Scheltens P

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