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This work was supported by Henan Provincial Medical Science and Technology Research Plan Provincial Key Project (No

Conversely, the GSSG concentration in the sample can be under estimated if the glutathione redox cycle is active or by mixed disulfide reactions with sulfhydryls other than GSH

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This peripheral restriction is fundamentally different from compounds like Semaglutide (a GLP-1 agonist that acts centrally to reduce appetite) or ghrelin-modulating agents that directly influence hunger hormones