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Endogenous Glucagon-like peptide-1 suppresses high-fat food intake by reducing synaptic drive onto mesolimbic dopamine neurons
Of the 611 participants, those using semaglutide had a mean body weight change of 16% compared to just 5.7% for those using the placebo
Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron
In a world with five distinct molecules each optimized for a different axis, the cost of being on the wrong one for a year is much larger than it used to be
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