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Some patients respond better to one over the other, which is why a personalized approach is important

Earlier studies demonstrated that the incretin effect of GIP was severely impaired in patients with uncontrolled T2DM ( In contrast, while the dose-response relationship between -cell responsiveness to glucose (expressed as the slope of the linear relation between insulin secretion rate and the glucose concentration) and GLP-1 levels in circulation is partially impaired a phenomenon referred as GLP-1 resistance ( Furthermore, a preclinical study conducted by Finan et al

Interaction of leptin and amylin in the longterm maintenance of weight loss in dietinduced obese rats

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