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In TRIUMPH-1, discontinuation due to adverse events occurred in: 1% of the 4 mg group 9% of the 9 mg group 3% of the 12 mg group 9% of the placebo group This demonstrates that average trial outcomes include participants who could not or did not continue their assigned treatment

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The reaction is catalyzed by the carnitine acetyltransferase (CrAT, EC:2.3.1.7), which is present in many cell compartments, including the cytosol, the matrix or mitochondria and peroxisomes, as well as the endoplasmic reticulum and nucleus [5, 83, 106]

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