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These medications work by mimicking the natural GLP-1 hormone, which plays a crucial role in regulating blood sugar, controlling appetite, and improving insulin sensitivity

4.3 Pharmacokinetic parameters in Sprague-Dawley rats after intravenous and intramuscular administration A total of 324 SD rats were randomly divided into five groups, including 66 rats in group one, 60 rats each in groups two to four, and 78 rats in group five, with each group comprising half male and half female subjects

Distribution and elimination were similar for oral, s.c

the same would apply to a woman using a combined oral preparation, as any reduction in efficacy would apply equally to the oestrogen and the progestogen and so not increase the risk of endometrial proliferation