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35 Because a number of bacterial proteins are Mn dependent, host-mediated Mn sequestration has the potential to disrupt bacterial pathogenesis

Months 3, 5, 7: Technical progress reports detailing technical progress made, tasks accomplished, major risks/mitigations, a technical plan for the remainder of Phase II (while this will normally report progress against the plan detailed in the proposal or presented at the Kickoff briefing, it is understood that scientific discoveries, competition, and regulatory changes may all have impacts on the planned work and DARPA must be made aware of any revisions that result), planned activities, trip summaries, and any potential issues or problem areas that require the attention of the DARPA PM