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doi: 10.1016/j.nutres.2011.04.001 46 LiuJ

In a clinical study involving patients with type 2 diabetes, an almond-based diet with a low-carbohydrate content, which had been previously shown to possess marked prebiotic properties [110, 111], resulted in augmentation of the number of SCFA-producing bacteria species, such as Roseburia , Ruminococcus and Eubacterium , which led to an increase in fasting blood GLP-1 levels and also promoted antidepressive effects after three months [112]

Moore prefers starting with conservative approaches oral options when available and tailoring the choice to the clinical target