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For instance, several age-related diseases including diabetes, dementia, metabolic syndrome, osteoporosis, cancer, arthritis, and cardiovascular diseases have been recognized as inflammatory disorders (Tan et al., 2015b

Metabolic modulation of acetaminophen-induced hepatotoxicity by osteopontin

Also, bile acids metabolism has been described as involved in atherosclerosis development: it is probably related to bacterial bile salt hydrolyzation, which can stimulate enlargement of atherosclerotic plaque through cholesterol accumulation and foam cell formation [68]

Characterization of the stress-inducing effects of homocysteine