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Two of these studies were conducted at 3T, using SPECIAL (Suri et al., 2017) and HERMES (Hupfeld et al., 2021), while the other two were at higher magnetic field strengths of 4T (Emir et al., 2011) and 7T (Lally et al., 2016), using MEGA-PRESS (Emir et al., 2011) and J-edited PRESS (Lally et al., 2016), respectively (Table 2)
The pattern of results, particularly the amplification of benefit at higher weight loss thresholds, is consistent with the hypothesis that HRT restores a metabolic environment that makes GLP-1 therapy more effective: improving insulin sensitivity, preserving lean mass, reducing the inflammatory burden that blunts metabolic responsiveness, and supporting the mitochondrial function that underlies energy regulation
FeelGood GLP-1 programs involve prescription medications