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And for women, it's 60 days for men, it's 90, which seems counterintuitive

The beneficial effect of caffeine in reducing memory impairment by regulating the expression of brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TrkB) or by regulating the expression of nuclear erythroid 2-related factor (Nrf2) and Toll-like receptor 4 (TLR 4)-induced glial cells-mediated neuronal cell death and neuroinflammation [46]