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As emphasized [11,12], counteraction occurred as a general shared effect, given the counteraction of the muscle weakness with abdominal aorta anastomosis, stroke, traumatic brain injury, spinal cord compression, neuroleptic catalepsy, amphetamine hypermobility, hyperkalemia, hypokalemia, hypermagnesemia, hyperlithemia, insulin hypoglycemia, local anesthetics, neurotoxin (parkinsogenic 1-methyl-4-phenyl-1,2,3,6-tetrahydrophyridine (MPTP), multiple sclerosis-like cuprizone), and tumor-induced muscle cachexia [11,12]

The disadvantage is that higher doses require large injection volumes

The impact of voluntary exercise on mental health in rodents: a neuroplasticity perspective