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Treatment with FOXO4-DRI led to the nuclear exclusion of active Ser15-phospho-p53 in senescent cells

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Trademark Information: BetaPower is a registered trademark of Danisco USA, Inc., Bio-Enhanced Na-RALA is a registered trademark of GeroNova, Inc., BIOSINT is a trademark of Sigma-Tau HealthScience USA., Setria is a registered trademark of Kyowa Hakko Bio Co., Ltd

A meta-analysis of seven studies including 1,757 participants with type 2 diabetes found that SGLT2 inhibitor therapy in combination with blood pressure medications (known as renin-angiotensin system blockers) was well-tolerated and resulted in greater improvement in blood pressure, glucose control, body weight, and indices of kidney function compared with the blood pressure drugs alone (Tian 2021)