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Most patients in the ACHIEVE trials who experienced GI symptoms found them manageable, and discontinuation rates due to side effects were in the 5-8% range, similar to injectable alternatives

Polymeric nanoparticles, hydrogels and microneedles Polymer NPs are typically composed of biodegradable materials such as PLGA, polylactic acid (PLA), polycaprolactone, and natural polymers like chitosan and gelatin [121]

sativa with other dermatological treatments (such as retinoids, vitamin C, or chemical peels) warrants further investigation to determine possible synergistic or antagonistic effects

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