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Genetic deletion of GSDMD (GSDMD / ) mitigates the size of atherosclerotic lesions in HFD-fed ApoE / mice

This activation significantly increased the Bcl-2-associated X protein (Bax)/B-cell lymphoma 2 (Bcl-2) ratio and cysteine-aspartate protease 3 (Caspase-3) expression, inhibited GPX4 and quinone oxidoreductase 1 (NQO1) expression, increased MDA levels, and promoted apoptosis, ferroptosis, and lipid peroxidation in NSC-34 cells

No es alergia, es reactividad qumica del metal de transicin