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The original published research on the pair came out of sports medicine, where elite athletes were using them to push back from soft tissue injuries faster

Endogenous glutathione levels can be enhanced through diet (increased consumption of protein, garlic, onions, and cruciferous vegetables) and supplements ((N-acetyl-cysteine, alpha-lipoic acid and others), which provide the body with the building blocks needed for its production

Combining these could potentially produce additive anti-inflammatory effects, which might be beneficial or could result in excessive immune suppression depending on the context

Exploring the mechanism of berberine intervention in ulcerative colitis from the perspective of inflammation and immunity based on systemic pharmacology