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Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025

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One of the three lead scientists, Dr Julia Moore-Vogel, joined me to discuss the LoCITT-T Trial

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GHK-Cu can be applied topically though penetration is limited

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The primary targets of KLOW

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