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Specifically IPRA (0.13 mg/kg), PIO (330 mg/kg), IPRA (1 mg/kg) combined with PIO (10 mg/kg), or a vehicle were given orally to diabetic mice with NASH for 4 weeks
It can be seen from studies that the gut microbiota is closely related to the development process of DKD, and the structure, number and function of the gut microbiota undergoes significant changes during this process, but its regulatory mechanisms are complex and diverse, and still not fully understood
(3) Its easy to understand why many people see growth hormone therapy as the fountain of youth