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TB500 has been evaluated for its potential effects on actin dynamics and cellular migration in animal models, but all published clinical research has used the full 43-amino-acid thymosin beta-4, not the TB500 fragment

This correlation was not significant in the healthy controls ( r = 0.13, p = 0.64, n = 15)

Its purported weight-loss mechanism centers on modulation of hypothalamic hunger centers during severe caloric restriction, though clinical evidence supporting efficacy remains limited

Before we investigated the effects of TAT-DAT NT in SHR rats, we hoped to rule out the possibility that TAT-DAT NT may act differently in rats compare to mice