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h , Homeostatic model assessment of insulin resistance (HOMA-IR)
Furthermore, ROS interacts with cellular transduction pathways like protein kinase C/extracellular signal-regulated kinases (ERK)/mitogen-activated protein kinase (MAPK) pathway that can affect cell growth, cell proliferation, differentiation, apoptosis and gene expression [10, 11]
In the absence of a structure showing the AR in antagonist conformation, the use of computer modeling has provided an entry point for structure-based drug design 197
(Trumbell, CT: Food & Nutrition Press
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