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Early research and patient reports have prompted interest in whether GLP-1 receptor agonists may help with cognitive changes commonly described as brain fog and with hot flashes, two symptoms frequently experienced during perimenopause and menopause

This leads to pulsatile GH release, which is essential for maintaining physiological GH patterns and reducing risk of receptor desensitization

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By addressing these broader factors, we can prevent obesity in the first place and make it easier to treat for those already affected." Specifically, Smith said that access to affordable whole foods that free from harmful additives, pesticides and dyes, was essential, and as was reversing the current food system's prioritization of "unhealthy, addictive ultra-processed foods." Other treatments also had a role to play, said Smith, including bariatric surgery which he said had been "shown to offer better long-term outcomes" than GLP-1 drugs