Given its ability to protect tissues and organs, EGCG has attracted attention for its potential to prevent and treat a wide range of chronic diseases, including cancer, cardiovascular conditions, neurodegenerative disorders, and metabolic diseases [17,22,23,24]
In the early stages of DKD, increased hyper-reabsorption and gluconeogenesis expose proximal tubular cells to hypoxia, resulting in mitochondrial dysfunction, increased oxidative stress and tubular injury ( Mitochondria is the primary organelle of in PTECs that is modulated to oxidative stress and hypoxic injury in the diabetic state ( Although there are a large number of in vitro and in vivo studies investigating the mechanism of hypoxia-induced renal tubular damage, due to the lack of non-invasive means, there are few clinical studies that have evaluated renal hypoxia in detail
AFRICA GLUTATHIONE MARKET SIZE, BY SKIN WHITENING, 2018-2032 (USD MILLION) TABLE 359
Impaired mental status is characterized by deterioration in mental status with psychomotor dysfunction, impaired memory, and increased reaction time, sensory abnormalities, poor concentration, disorientation and coma
