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CAT is able to scavenge exogenous and high endogenous peroxide levels [59, 60, 70], while GPx and Prx2 appear to scavenge endogenous and low peroxide levels [59, 70, 73]

Although the current nomogram is conservative and has proven to be a reliable guide for NAC treatment after acetaminophen poisoning [64], treatment decisions based on a single measurement may not assess the risk completely, as patients who were initially stratified as below the treatment line, can cross the treatment threshold following overdose [65]

A., Emon, N

This should be set against the evidence from studies in biofilms that NAC may enhance the activity of antibiotics in respiratory airway infections by inhibiting and/or disrupting biofilm formation (reviewed in [25])