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Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder

While this molecule can be found in all human tissues, youll find some of the highest concentrations in the liver

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Recent studies demonstrate that gut microbiota modulate dietary tryptophan metabolism, producing bioactive metabolites such as indole derivatives, kynurenines, and serotonin that influence neurophysiology, mood, cognition, and the gutbrain axis (Yuxuan et al., 2026