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Since semaglutide reduces appetite and helps control calorie intake, increasing physical activity becomes an important part of maintaining muscle mass and increasing overall metabolic burn

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Magn Reson Med 74:15301542 Demarest TG, Schuh RA, Waddell J, McKenna MC, Fiskum G (2016) Sex dependent mitochondrial respiratory impairment and oxidative stress in a rat model of neonatal hypoxic-ischemic encephalopathy