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Adenosine increases the synthesis of procollagen-1, maintaining skin density, smoothness and elasticity, slows down the aging process, and strengthens the extracellular matrix

The antinociceptive effect of morphine was shown for a short period, but morphine might have contributed to wound healing

A personalised approach often leads to better and faster results

These new findings encourage a novel working hypothesis for further research, that a chemical-modification mechanism enables transformation of HGF through interaction or reaction with LASSS under physiological conditions, resulting in the retention of HGFs biological activity after exposure to peroxynitrite, at least until an enhanced form of HGF undergoes metabolic turnover in vivo