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Because of this dual-purpose nature, most supplements require a Letter of Medical Necessity (LMN)

However, these results come from different trials, different populations, and different timeframes, so they cant be directly compared

Chitosan-coated nanoparticles, in particular, are biodegradable, non-toxic, and capable of sustaining the release of polyphenols at the sperm membrane interface, thus enhancing their protective potential during cryopreservation 19

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