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GLP-1 receptor agonists and the dual agonist tirzepatide modulate appetite, satiety, and gastric emptying, with evidence from STEP (NEJM 2021), SURMOUNT (NEJM 2022), and SURMOUNT-OSA (NEJM 2024)

However, another meta-analysis of patients with type 2 diabetes mellitus complicated with sarcopenia showed that GLP-1 receptor agonists had no significant effect on lean body mass and skeletal muscle index [56]

Supplemental Collagen The collagen obtained from bone broth is primarily in the form of gelatin collagen that has been partially hydrolyzed by the prolonged heat of simmering but not broken down as completely as enzymatically hydrolyzed collagen (collagen peptides) [1]

We calculated the Gini index to measure differences in prescription rates in 2024 by sex, age, self-reported race and ethnicity, social vulnerability index, rural-urban commuting area, and insurance type