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Your best choice depends on how you manage routine, side effects, costs, and whether you can combine medication with good habits that preserve muscle and hydration

The safety and efficacy of once-weekly glucagon-like peptide-1 receptor agonist semaglutide in patients with type 2 diabetes mellitus: a systemic review and meta-analysis

SGECs exhibit polarization along the apicalbasal axis, with the apical pole facing the lumen and the basal pole directed towards the deep connective tissue [39]

2.5 mg to 15 mg maintenance Mean weight loss (standard dose) Wegovy: ~13.7% at 72 weeks (SURMOUNT-5) Mounjaro: ~20.2% at 72 weeks (SURMOUNT-5) Available in Ireland Wegovy: Yes - private prescription Mounjaro: Yes - private prescription HSE reimbursement Wegovy: Not yet (NCPE review ongoing) Mounjaro: Not yet Access and Cost in Ireland in 2026 Both Wegovy and Mounjaro are available in Ireland on private prescription