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Testosterone: Functions and Importance Testosterone is the primary male sex hormone, though women also produce it in smaller amounts

It is essential for the catalytic activity of several classes of histone deacetylases (HDACs), as well as for the structural integrity and function of certain histone acetyltransferases, which together govern chromatin compaction and gene expression, and of DNA methyltransferases (DNMTs), which influence DNA methylation and processes such as lineage commitment and genomic imprinting 11

First, it acts as a glutathione-sparing agent by immediately attacking free radicals

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