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Similarly, another phase III clinical trial using higher doses of vitamin E (5,000 mg) did not improve the quality of life or disease progression in ALS patients compared to controls (Graf et al., 2005)

Patients whose HbA1c had already become worse than their pre-GLP-1 baseline at three months were most likely to remain in that category at twelve months (50%), though 25% had improved to below their pre-GLP-1 level by twelve months