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In chemotherapy-sensitive patients, Keap1 (Kelch-like ECH-associated protein 1) binds to NRF2 and mediates NRF2 ubiquitination via the Cul3-E3 ligase complex, promoting its degradation and maintaining NRF2 at low levels [32]

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One produces roughly 6% body weight loss in clinical trials

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Similar content being viewed by others Introduction The oral squamous cell carcinoma (OSCC) is the most common cancer in India, with highest occurrence in the north-eastern part of the country 1

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